Introduction

Proteomic, genomics and post genomics could benefit from materials science and nanotechnology, which may offer innovative solutions to some of the open questions, i.e.:

  • low cost and high throughput gene or protein expression profiling methods;
  • high reproducible methods to analyze specific antigen expression patterns and protein interactions in cells and sera at very low concentration;
  • perform genotyping and haplotyping by using probes detectable on a single DNA strand at distances as low as 10 nucleotides apart;
  • mass selection and mass characterization of macromolecules by using nano/molecular sieves

Recent advances in materials science and nanotechnologies have been emerging with precise control over material chemical, physical and morphological properties and with the enhanced capability to immobilize into/within synthetic platforms molecular signal for particular moieties detection.

The objective of the research will be realization of new biosensor for a fast, high throughput and multiple detection of biomolecules by building into 3D platforms biomolecules recognizing moieties.